• Evidence Base

Where Expertise Meets Evidence.

MedScience Research Group, along with its division, AllergiEnd®, aims to enhance our client's quality of life through research, evidence-based diagnostics, innovative intervention, education, promotion, and distribution, while improving the physician’s medical practice. Our diagnostic systems and allergen immunotherapy methods are known for achieving meaningful, long-term allergy and asthma improvements throughout the population we serve.

What is Evidence-Based Medicine (EBM)?

Evidence-based medicine (EBM) is the conscientious, explicit, and judicious use of current best evidence in making decisions about health strategies to promote the health of individuals, communities, and populations. The practice of EBM means integrating local expertise with the best available external evidence yielded by systematic research. EBM requires conducting cross-disciplinary literature searches, applying rules of evidence and appraisal of study quality, and selecting the most effective programs.


EBM asks the practitioner to present to the patient consumer a reliable summary of the treatment area of interest, including its strengths, weaknesses, and recommendations. Clinicians use research by integrating it with their clinical expertise and their patients’ expectations. The incorporation of patient values and clinical expertise in EBM partly recognizes that many aspects of health care depend on individual factors. These include variations in unique physiology and pathology as well as quality-of-life and value-of-life judgments.


These factors are only partially subjected to scientific inquiry and sometimes cannot be assessed in controlled experimental settings. The application of available evidence is, therefore, dependent on patient circumstances and preferences. It remains subject to input from personal, political, philosophical, religious, ethical, economic, and aesthetic values leading to more evidence-based healthcare as a whole.


EBM has evolved from the critical need to bridge the gap between research and practice. EBM applies research information (evidence) to clinical practice, emphasizing the importance of using quantitative (as well as qualitative) evidence in the art of clinical decision making. It aims to make decision-making more structured and objective by better reflecting the evidence from research. By introducing the use of research information in clinical decision-making, particularly from clinical epidemiology, EBM has driven a transformation of clinical practice and medical education.

References and Sources 

Allergies and Asthma
Skin Testing
Allergen Immunotherapy
Lifestyle Medicine
Original Research
Allergies and Asthma

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Skin Testing

Bagg et al. Systemic reactions to percutaneous and intradermal skin tests World Allergy Organisation Journal 2007

Allergen Immunotherapy

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Cox et al. Allergen Immunotherapy: A practice parameter third update. J Allergy Clin Immunol. January 2011.

Lifestyle Medicine

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Moreira et al. A World Allergy Organization international survey on physical activity as a treatment option for asthma and allergiesWorld Allergy Organization Journal 2014 7:34.


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Taback SP, Simons ER. Anaphylaxis and vitamin D: A role for the sunshine hormone? J Allergy Clin Immunol.  2007;120:128-130


Weiss S. Bacterial Components plus vitamin D: The ultimate solution to the Asthma (autoimmune disease) Epidemic? .J Allergy Clin Immunol . 2011 May ; 127(5): 1128–1130

Original Research